Department of Pharmacognosy

About the Department

Pharmacognosy is an essential domain of modern pharmaceutical science deals with the natural medicines adopting traditional medicine based approaches with a multidiscipline. Many phyto constituents still exist as irreplaceable therapeutic entities in the field of modern therapy. To address the safety concern, researchers are looking for a potent, safe, consistent phytochemicals from natural origin. The department of Pharmacognosy, College of Pharmaceutical Sciences provide extensive knowledge in theory as well as practical in undergraduate level. The students are trained and skilled for herbal drug development, regulatory polices, quality control aspects.

Core research Area

• Study of the medicinal properties of natural products, for the purposes of drug discovery and understanding how dietary supplements work.
• Phytochemical analysis of plant and herbal products, pharmacological screening of natural products.
• Development and use of analytical methods for quality control of natural products.
• Cosmetic application of natural products
• Formulation and development of Natural Product

Research Projects

• Phytochemical screening and in- vitro anthelmintic activity of Solanum species.
• Anti-venom potential of methanolic extracts of Leucas aspera and Cordia macleodii against saw scaled and Krait venoms.
• In vitro assessment of antioxidant and cytotoxicity studies of Brown algae.
• Effect of kamarks gond on metformin tablet formulation.
• HPLC analysis of methanolic extract of Ricinus communis using quercetin, gallic acid and catechin along with pharmacognostic studies.
• Brief insight of invitro pharmacological screening of Dalbergia leaf extract.
• Formulation and evaluation of a mouth dissolving polyherbal film for dental cairies.
• Phytochemical characterization and in vitro cytotoxic study of Dalbergia stem extract.
• Formulation and Evaluation of antidandruff and antimelanogenic soap of Phyla nodiflora.
• Nutraceuticals for The Management Of Immune Function and Inflammation Associated Metabolic Disorders.
• Biological evaluation of macroalgae in Autoimmune and Allergic Skin Diseases.
• In silico -screening, phytochemical investigation and pharmacological evaluation of macro algae as possible neuroprotectives.

Facilities:

• BioRad – Elisa reader
• Hot air oven
• Compound Microscope
• Muffle furnace
• Centrifuge
• Iceflaker
• Soxhlet apparatus

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Publications

• Iswar Hazarika, K.M. Geetha, P. Sivakami Sundari. Neuroprotective effect of Hydrocotyle sibthorpioides against monosodium glutamate-induced excitotoxicity Natural Product Research, DOI: 10.1080/14786419.2022.2057493
• Iswar Hazarika, K.M. Geetha, P. Sivakami Sundari, Anju Das. The modulatory effect of Hydrocotyle sibthorpioides in attenuating the aluminium chloride induced neurotoxicity in rat brain. Adv. trad. Med. 2021; 22(1): 207-219. DOI:10.1007/s13596-020-00526-7
• Iswar Hazarika, K.M. Geetha, P. Sivakami Sundari, Divya madhu. Acute oral toxicity evaluation of extracts of Hydrocotyle sibthorpioides in wister albino rats as per OECD 425 TG.Toxicology Reports. 2019(6) 321-328. doi: 10.1016/j.toxrep.2019.04.001
• M. Sennappan, P. Murali Krishna, R. Ranganathan, P. Sivakami sundari. Synthesis, characterization, nucleic acid interaction and photoluminescence properties of (E)-(2-(2-hydroxybenzylidene)hydrazinyl)(pyridine-4-yl)methaniminium Mn(II), Co (II), Ni(II), Cu(II) and Zn(II) complexes. Journal of Molecular Structure. 2019. 86-91. DOI:10.1016/j.molstruc.2018.10.087
• P. Sivakami sundari, Shanaz Banu, V. Murugan, N. Dhanashree. GC MS/MS Analysis of bioactive compounds in alcoholic seed extract of Gauzuma ulmifolia Lam Pharmacogn J. 2018; 10(1):194-197.
• Sushma S Murthy, Sharath, SujanGananpathy P.S., Sivakamisundari P, Preetham J. Pharmacognsotical and  Phytochemical Evaluation of Curcuma angustifolia roxb. (Rhizome) Indigenous Ethno-Medicinal Plant used by Tribal Soliga Community of Biligirirangana Hills. Ijppr. 2015. 7(4): 820-24. https://www.researchgate.net/publication/283465339
  

Ongoing Projects

• Coccinia grandis fruit jelly as possible antihyperlipidemic nutraceutical.
• Extraction of phytoconstituents from natural product.
• Separation of mixtures using chromatographic techniques