mahesh
Faculty Name: Mr. AR Mahesh
Designation : Assistant Professor

Mr. AR Mahesh started his teaching career in 2012 as a lecturer. He holds an M.Pharm(Pharmaceutical Chemistry) from RGUHS, MBA in Pharma Business Management from ICFAI, Tripura and currently working in DSU and also perusing his Ph.D under RGUHS. He has published 10 Publications in International and National Journals. Hehas been invited for a number of guest lectures on various topics in other institutes like Oxbridge College of Pharmacy, KCP, PESCP, RGUHS.Recently he completed a continuous education course on 1D and 2D NMR Spectroscopy-Applications in Structure Biology securing Grade-A in Indian Institute of Science, Bengaluru.

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Recent Awards:

  1. “Academic Excellence Award 2019” by ‘Institute of Scholars’ recognized by Ministry of MSME, India, in recognition of valuable contribution to the academic community and students.

Editorial Board Member:

  1. Rubatosis Publications, since 21/03/2018.
  2. International Journal of Multidisciplinary Research and Publications, since 21/04/2018

Professional Registration Certification:

  1. Registered Pharmacist under Karnataka State Pharmacy Council, India since 28-Mar-2009.
  2. Lifetime Member of Institute of Scholars, Recognized by Ministry of MSME, since September, 2019.
  3. Member of ISPOR, Since September, 2019
  4. Life Member of Foundation for Health and Environment Research, Since September, 2019

Research:

  1. Research Interests
    • Synthesis of Novel Anticancer agents,
    • Molecular Modelling and Docking studies of novel anticancer agents.
  2. Research Grants: Annexture-3
    Sl. No. Project Title Sponsoring Agency Date of Sanction Project Cost PI/Co-PI/Ongoing/ Completed
    1 ‘Synthesis and evaluation of Nitrogen Mustard linked benzofuranone derivatives as possible alkylating anticancer agents’ RGUHS 06/01/2016 7,00,000 Co-PI/Ongoing
  3. Industry interaction:
    • Completed one year “Internship programme” and dissertation project in Department of Phytochemistry research at Natural Remedies Pvt., Ltd., Bangalore.
  4. Publications
    • National/International Publications: 16 (Annexture-4)
    • Poster Presentations in Conferences: 05 (Annexture-5)
    • Conferences Attended: 32 (Annexture-6)

Other Achievements:

  1. Proficiency course in 1D and 2D NMR Spectroscopy: Applications in Structure Biology. IISc, Bengaluru (Jan-May, 2016) [secured A-Grade]
  2. Resource person in “Soft Skills and Leadership” in Krupanidhi College of Pharmacy on 19-06-2012 for UG and PG students of Pharmacy.
  3. Resource person in “Short Course in Education methodology” Conducted by RGUHS in collaboration with APTI for teachers of Pharmacy Faculty.

    Roles:

    • Headed a training session on “Question paper Setting” on 21st Mar, 2016
    • Headed a training session on “Objective structured practical Examination” on 29th Mar, 2016.
    • Evaluator for various micro teaching sessions of the course.
  4. Resource person in Guest Lecture was given on the topic “The Patents Act” at PES College of Pharmacy on 24th Mar, 2016.
  5. Resource person in five days Faculty Development Program on “Managing Stress in Teaching Profession” held at Dayananda Sagar University, Bengaluru from 9th -13th January, 2017
  6. Resource person in Guest Lecture organized by PES College of Pharmacy on 24th Mar, 2017 Topic “Magic remedies and objectional advertisements act”.
  7. Resource person in Guest Lecture organized by College of Pharmaceutical Sciences, Dayananda Sagar University on 27th Oct, 2019, Topic: Application of Artificial Intelligence in Healthcare.
  8. E-Poster Evaluator, in RGUHS sponsored National Conference on “Cosmeceutical Technology” RR College of Pharmacy on 13th and 14th March, 2020.

Present Research Work

An attempt will be made to synthesize some heterocyclic compounds containing Nitrogen mustards linked to Aurones and to study their possible cytotoxicity and anticancer activity will be evaluated.

  • Synthesis of Nitrogen mustard linked Aurones based on reported methods.
  • Purification and characterization of the structures of newly synthesized compounds by TLC, UV, FTIR ,1H NMR, 13C NMR and CHN analysis methods

The rapid assembly of molecular diversity is important goal of Synthetic Organic Chemistry and one of the key paradigms of modern drug discovery. One approach to address this challenge involves development of newer molecules in which a few reactants are combined together in a single reaction flask to generate a product incorporating most of the atoms contained in the starting materials. Diversity can be achieved either by varying each component or changing the reaction conditions. The biological activity and development of novel drugs with unique properties. The Aurones and Nitrogen mustards possess significant pharmacological and biological activities such as alkalyting, cytotoxic, antitumor, anti-inflammatory and other diseases.

Publications

  1. Vimal John Samuel, Komal Kulkarni, Agasa Ramu Mahesh, Drug Utilization Pattern of Cephalosporins in In-Patient Departments of Tertiary Care Hospital. Journal of Pharmaceutical Sciences and Research. 2019;11(6), 2398-2401.
  2. Vimal John Samuel, AgasaRamu Mahesh, VedigounderMurugan, Phytochemical and pharmacological aspects of Tephrosia genus: A brief review. Journal of Applied Pharmaceutical Science, 2019; 9(03), 117-125
  3. Vimal John Samuel and A. R. Mahesh , In- Vitro Antioxidant Properties, Acute And Subacute Toxicity Studies Of TephrosiaCalophylla On Albino Wistar Rats. International Journal of Pharmaceutical Sciences and Research, 2019; 10(6): 1000-07.
  4. KB Premakumari, AR Mahesh, V Murugan, V Ezhilarasan. Simultaneous estimation of paracetamol and zaltoprofen in pharmaceutical dosage form by HPTLC. http://www.anvpublication.org/Download_Acceptance.aspx?PID=1916200209899803.
  5. AsalTanhaeiSaeid, Fereshteh Jaferi, AR Mahesh, Ali Alipour, Komal Kulkarni, A Retrospective, Observational Study Effect of Polypharmacy and Drug Interactions in Elderly Patients. Saudi Journal of Medical and Pharmaceutical Sciences, 2019; 5(2): 147-153.
  6. Kalpana Divekar, Sushma KR, AR Mahesh, Selectivity of Plants and Microbial Reduction of Ketones. Sch. Acad. J. Pharm. Jan 2018;7(1):26-35.
  7. V Murugan, Shrideep Bhattacharjee, AR Mahesh, Synthesis and characterization of N-N- {Bis(2′-Chloroethylamino)- nitroso}-2-benzylidene-1-benzofuran derivatives as antileukemic agents. Am. J. Pharm Health Res, 2016;4(7).
  8. Mahesh AR, Samuel YamtaMshelia and Vimal John Samuel, Therapeutic activities of Aurone, An appositely active molecule-A Review. World Journal of Pharmacy and Pharmaceutical Sciences. 2016: 5(7):668-82.
  9. Mahesh AR, Murugan V, Synthesis of a biologically pertinent molecule, Aurone-An extensive review. European Journal of Biomedical & Pharmaceutical Sciences. 2016: 3(1):112-16.
  10. M Somashekhar, Naira Nayeem, Mahesh AR. Botanical study of four ficus species of family Moraceae: A Review. International Journal of Universal Pharmacy and Bio Sciences, 2013; 2(6):558-570.
  11. Somashekhar M, Mahesh AR. Synthesis and antimicrobial activity of piperazine derivatives. Am.J.Pharm Tech. 2013; 3(4):640-648.
  12. Somashekhar M, Mahesh AR, Basavaraj Sonnad. Synthesis and antimicrobial activity of of 4-(morpholin-4-yl) benzohydrazide derivatives. World Journal of Pharmacy and Pharmaceutical Sciences, 2013; 2(4):2011-2020.
  13. Manish K, Mahesh AR, Somashekhar M.   International Journal of Pharma Research and Review, 2013; 2(8).
  14. Mahesh AR, Ranganath Mk, Harish Kumar DR, Enrichment of Flavanoids from the methanolic Extract of BoerhaaviaDiffusa Roots by Partitioning Technique. Research Journal of Chemical Sciences, 2013:3(1),43-47.
  15. Hitesh HS, Mayukh B, Mahesh AR. Isolation and characterization of chemical constituents of aerial parts of Lantana Camara. 01 2012; 1(6):198-207.
  16. AR Mahesh, Harish Kumar, K, Raviraj Anand Devkar. Detail Study on BoerhaaviaDiffusa Plant for its Medicinal Importance-A Review, Research Journal of Pharmaceutical Sciences. 2012; 1(1):28-36.

Presentations

  1. Presented a poster “Simultaneous estimation of paracetamol and zaltoprofen in pharmaceutical dosage form by HPTLC” in international conference Krupacon-2018, Krupanidhi College of Pharmacy, Bengaluru, 2018.
  2. Presented a poster “Neonatal Infections - A Review” in National Conference on "Advances in Pharmacy Practice", NET College of Pharmacy, Raichur. 28th-29th Nov, 2013.
  3. Presented a poster “Synthesis and Hydrolytic kinetic study of derived antihypertensive codrugs” 3rd International Pharmaceutical Conference on “Current status and future perspective in Pharmaceutical Sciences”, PESCP.19th-20th August 2011.
  4. Presented a poster “Synthesis and Hydrolytic kinetic study of some Antihypertensive Co-Drugs” in 63rd IPC, Bangalore. 16th -18th December 2011.
  5. Presented a poster “Synthesis of some Co-Drugs of Propranalol and other antihypertensive drug via Anhydride Bridge and their hydrolytic kinetic study” in Indo-US Symposium on “Frontiers in Medicinal Chemistry and Drug Discovery” April 21st-23rd 2011.

Seminars/ Conferences/ Workshops Attended:

Sl No. Date Place Title Organizing Agency No.Of Days
1 13-03-2020, 14-03-2020 RR College of Pharmacy, Bengaluru Cosmeceutical Technology RGUHS, RR College of Pharmacy, Bengaluru 2
2 25-03-2019 Vishveshwarapura Institute of Pharmaceutical Sciences Short Course on Teaching Methodologies RGUHS, Karnataka 2
3 16-02-2019 RR College of Pharmacy National Workshop on Computer Aided Drug Development RGUHS, RR Institutions, Bengaluru 1
4 22-01-2019 Zastra Innovations One Day International Symposium on Streamlining Drug Design Regenta Palace, Bengaluru 1
5 17-12-2018 Dayananda sagar University Challenges and Opportunities for clinical pharmacists Dayananda Sagar University, Bengaluru 2
6 12-10-2018 Krupanidhi College of Pharmacy,Bengaluru International Conference on drug development and clinical research: current scenario and opportunities Krupanidhi College of Pharmacy, Bengaluru 2
7 29-08-2018 Dayananda Sagar University Targeted Cancer Therapy and ResearchAdvances and Challenges Dayananda Sagar University, Bengaluru 1
8 19-08-2018 College of Pharmaceutical Sciences Targeted Cancer Therapy & Research- Advances & Challenges Dayananda Sagar University 1
9 25-04-2018 College of Pharmaceutical Sciences, DSU Career Opportunities in Clinical Research & Pharmacovigilance Dayananda Sagar UNiversity 1
10 15-02-2018 Ramiah University Application of computational tools in drug design & formulation development Ramaiah University 1
11 14-07-2017 Krupanidhi College of Pharmacy Workshop on sensitisation of syllabus for B.Pharm & M.Pharm Courses Pharmacy Council of India 1
12 09-01-2017 College of Pharmaceutical Sciences, Dayananda Sagar University Managing Stress In Teaching Profession College of Pharmaceutical Sciences, Dayananda Sagar University 5
13 14-11-2016 Goa College of Pharmacy, PanjimGoa 1.5 Day Professional Development Program: Intellectual Property for Industry and Academia Professionals: Training the Trainers G-CEIP 2
14 05-08-2016 BMS College of Engineering, Bengaluru One Day National Symposium on Fundamentals of Drug Discovery Process:Industrial Perspective Department of Chemistry & Biotechnology,BMSCE 1
15 26-02-2016 KLE University, Bengaluru Workshop on Interpretation of Spectra- A Practical Approach KLE University 1
16 01-01-2016 IISc 1D &2D NMR Spectroscopy: Applications in Structure Biology CEE- Proficience Programme-IISc 20
17 05-10-2015 Al-Ameen College of Pharmacy, Bengaluru National Level Workshop on Rational Approach on Drug Design and Discovery using CADD Vlife, Al-Ameen College of Pharmacy 2
18 29-09-2015 Rajiv Gandhi University of Health Sciences Research Methodology CME & Workshop RGUHS, Karnataka 2
19 29-11-2013 NET Pharmacy College, Raichur National Conference on Advances in Pharmacy Practice RGUHS, Karnataka 2
20 16-09-2013 Acharya & BM Reddy College of Pharmacy,Bengalur FDP on Computer Aided Drug Design ACTE 13
21 16-12-2011 Bangalore International Exhibition Centre 63rd Indian Pharmaceutical Congress Indian Pharmaceutical Congress 3
22 14-12-2011 Al-Ameen College of Pharmacy, Bengaluru Pre-Conference workshop on the basic concepts of Scientific Research and Scientific Communication of 63rd IPC Indian Pharmaceutical Congress 2
23 19-08-2011 PES College of Pharmacy Current Status & Future Perspective in Pharmaceutical Sciences DST, CSIR, ICMR, RGUHS, AICTE 2
24 21-04-2011 JSS University, Mysore Indo-US Symposium on Frontiers in Medicinal Chemistry and Drug Discovery American Chemical Society 3
25 11-02-2011 Dayananda Sagar College of Pharmacy Principles, Applications and Current Developments in 1H NMR, 13C NMR and aMass Spectroscopy DST, RGUHS 2
26 03-12-2010 Dayananda Sagar College of Pharmacy Standardization and evaluation of Herbal Drugs RGUHS, Karnataka 1
27 21-05-2010 DSCDS & Hospital Infection control in Health Care Setting Indian Dental Association 1
28 31-03-2010 Dayananda Sagar College of Pharmacy Recent Trends in Molecular Pharmacology and Drug Designing DST 2
29 02-02-2008 Dayananda Sagar College of Pharmacy Clinical Research- Advances and Opportunities RGUHS 1
30 14-12-2007 Dayananda Sagar College of Pharmacy Synthesis of Heterocyclic Compounds using Microwave Technique RGUHS, Karnataka 1